Cystatin GFR better marker than creatinine GFR for accurate prediction of renal dysfunction in diabetic patients: A tertiary care centre study

Cystatin C versus creatinine-based GFR formula in CKD patients

Introduction. Glomerular Filtration Rate (GFR) is the main tool to assess kidney function. Some experts suggest cystatin C as a more precise and accurate indicator than creatinine to calculate GFR. This study is designed to assess if cystatin C is more helpful in early diagnosis and better follow-up of Chronic Kidney Disease (CKD) patients who may benefit more from appropriate and timely manage...

Determining an accurate method to estimate GFR in renal transplant recipients with stable serum creatinine levels

Introduction:Detecting renal allograft dysfunction early will allow timely diagnosis and treatment. There is no objective recommendation by national kidney societies for glomerular filtration rate (eGFR) estimation in post-transplant setting. 99mTc-DTPA Technetium-99m Diethylene triamine penta acetic acid) renogram can identify early renal dysfunction much before ser...

Serum cystatin C measured by automated immunoassay: a more sensitive marker of changes in GFR than serum creatinine.

Serum cystatin C has been suggested as a new marker of GFR. For the introduction of this marker into clinical use a rapid and automated method is required. We have developed and validated an assay for serum cystatin C using latex particle-enhanced immunoturbidimetry. Intra- and inter-assay precision were < 3% and < 5% across the assay range. Analytical recovery was 93 +/- 3.8% and no lack of pa...

Need of standardization for creatinine and cystatin C-based GFR equations in renal transplantation.

Sir, We read with interest the detailed comparison of various creatinineand cystatin C (Cys C)-based equations to determine GFR in patients after kidney transplantation [1]. This publication provides a comprehensive overview of the most commonly used equations and importantly, applies inulin clearance as gold standard GFR measurement. The authors conclude that creatinine-based formulae are not ...

Is combined cystatin C and creatinine based equation better in predicting GFR?